Higgs Lab


Henry N. Higgs, Ph.D.
THE BOSS
Professor, Department of Biochemistry and Cell Biology
John LaPorte Given Professor in Cytology
B.A., Lafayette College, 1987
Ph.D., University of Washington (Glomset Lab), 1996
Post-Doc, Salk Institute for Biological Studies (Pollard Lab), 2001

Miriam Lee
POST-DOC
B.S., Chonnam National University, Gwangju, South Korea, 2012
M.Sc., Gwangju Institute of Science & Technology, 2011
Ph.D., Gwangju Institute of Science & Technology, 2017
My research focuses on the functions of INF2-CAAX, as well as acetylated actin in regulating mitochnodrial dynamics.

Sukrut Kamerkar
POST-DOC
B.S., Mumbai University, 2012
M.Sc., IISER Pune, India, 2019
Ph.D., IISER Pune, India 2019
My work investigates mitochondrial cristae architecture in humans, with an emphasis on an exciting but poorly understood protein of the mitochondrial intermembrane space-LACTB.

Will King
RESEARCH ASSISTANT
B.S., Birmingham-Southern College, 2015, Phi Beta Kappa
M.Sc., Johns Hopkins University, 2023
My work focuses on understanding the function and regulation of actin modifying proteins and how they are regulated in disease states.

Ziwei She
GRADUATE STUDENT

Berglind Bjarnadóttir
GRADUATE STUDENT
B.S., Guangzhou University of Chinese Medicine, 2016
M.Sc., Peking University, Beijing, China
I am figuring out how actin polymerization contributes to metabolic switching between oxidative phosphorylation and glycolysis in response to mitochondrial damage.
Certificate, Reykjavík College of Music, 2021
B.S., University of Iceland, 2024
I am currently working to identify actin binding proteins using whole cell proteomics which we hope will define the "actinome." I am also working to biochemically characterize actin binding proteins which affect actin polymerization.

Isaiah Nordine
GRADUATE STUDENT
B.A., Luther College, Decorah, IA 2024
My research investigates how different actin binding proteins regulate disassembly of actin filaments in cells. Additionally, I am studying how mutations in these proteins contribute to FSGS, an inherited kidney disease.

Rocky
LAB GUARD ROCK

Drew Melching
Undergraduate '29
I was painted by a lab member's niece in 2021 and made the trek to Dartmouth from Alabama. In my spare time, I'm quite fond of silent contemplation and stillness. I never shy away from taking on the hard things in life!
COLLABORATIONS
The Higgs lab works closely with Martin Pollak at Beth Israel Deaconess Medical Center, and Ed Usherwood at Dartmouth's Geisel School of Medicine, microbiology and immunology.
Within the Dartmouth community, Harry is also a mentor for the interdisciplinary BioMT project, an NIH sponsored COBRE grant to support junior faculty. Harry is also a member of the Dartmouth Cancer Center.